Vesa M Olkkonen Selected Research

oxysterol binding protein

12/2019	ORP4L couples IP3 to ITPR1 in control of endoplasmic reticulum calcium release.
12/2016	ORP4L Facilitates Macrophage Survival via G-Protein-Coupled Signaling: ORP4L-/- Mice Display a Reduction of Atherosclerosis.
2/2015	OSBP-related protein 3 (ORP3) coupling with VAMP-associated protein A regulates R-Ras activity.
12/2012	ORP10, a cholesterol binding protein associated with microtubules, regulates apolipoprotein B-100 secretion.
8/2009	OSBPL10, a novel candidate gene for high triglyceride trait in dyslipidemic Finnish subjects, regulates cellular lipid metabolism.
3/2008	The R-Ras interaction partner ORP3 regulates cell adhesion.

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Vesa M Olkkonen Research Topics

Disease

10	Insulin Resistance 01/2022 - 12/2004
9	Non-alcoholic Fatty Liver Disease 03/2020 - 12/2010
8	Atherosclerosis 12/2018 - 01/2004
6	Neoplasms (Cancer) 01/2022 - 03/2008
6	Inflammation (Inflammations) 01/2020 - 09/2012
5	Obesity 01/2022 - 04/2011
4	Fatty Liver 11/2019 - 12/2010
4	Hepatocellular Carcinoma (Hepatoma) 01/2019 - 05/2012
3	Hyperinsulinism (Hyperinsulinemia) 01/2022 - 04/2012
3	Cardiovascular Diseases (Cardiovascular Disease) 01/2020 - 04/2014
3	Weight Loss (Weight Reduction) 11/2017 - 07/2011
3	Liver Diseases (Liver Disease) 04/2016 - 07/2011
2	Simpson-Golabi-Behmel syndrome 01/2022 - 01/2019
2	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 12/2019 - 01/2016
2	Coronary Artery Disease (Coronary Atherosclerosis) 01/2019 - 01/2016
2	Metabolic Diseases (Metabolic Disease) 11/2017 - 01/2016
2	Familial Combined Hyperlipidemia (Combined Hyperlipidemia, Familial) 01/2016 - 08/2009
1	Myocardial Ischemia (Ischemic Heart Diseases) 01/2022
1	Mitochondrial Diseases (Mitochondrial Disease) 01/2022
1	Heart Failure 01/2022
1	Hypoxia (Hypoxemia) 01/2020
1	Hearing Loss (Hearing Impairment) 01/2019
1	Leukemia 01/2019
1	Osteoporosis 01/2019
1	Hyperlipoproteinemia Type II (Familial Hypercholesterolemia) 01/2018
1	Morbid Obesity 11/2017
1	Protein Deficiency 07/2017
1	Chronic Disease (Chronic Diseases) 01/2017
1	Type 2 Diabetes Mellitus (MODY) 04/2016
1	Sleep Deprivation 01/2016
1	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL) 01/2016
1	Urinary Bladder Neoplasms (Bladder Cancer) 12/2012
1	Dyslipidemias (Dyslipidemia) 12/2012
1	Peripheral Arterial Disease 12/2012
1	Body Weight (Weight, Body) 10/2012
1	Overweight 10/2012
1	Metaplasia 09/2012

Drug/Important Bio-Agent (IBA)

14	Proteins (Proteins, Gene)FDA Link 01/2022 - 11/2002
10	LipidsIBA 12/2020 - 11/2005
8	Triglycerides (Triacylglycerol)IBA 01/2019 - 08/2009
7	Insulin (Novolin)FDA Link 01/2022 - 12/2004
6	MicroRNAs (MicroRNA)IBA 01/2022 - 04/2011
6	Fatty Acids (Saturated Fatty Acids)IBA 01/2022 - 12/2010
6	oxysterol binding proteinIBA 12/2019 - 03/2008
6	CholesterolIBA 12/2018 - 01/2004
5	Glucose (Dextrose)FDA LinkGeneric 12/2020 - 12/2004
4	Messenger RNA (mRNA)IBA 01/2022 - 01/2004
4	Lipoproteins (Lipoprotein)IBA 01/2020 - 09/2013
3	oxidized low density lipoproteinIBA 12/2020 - 01/2016
3	Glycerol (Glycerine)FDA LinkGeneric 01/2020 - 12/2010
3	OxysterolsIBA 12/2016 - 01/2004
2	Phosphatidylinositols (Phosphatidylinositol)IBA 01/2022 - 10/2012
2	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 12/2020 - 01/2017
2	Lipoprotein Lipase (Diacylglycerol Lipase)IBA 01/2020 - 09/2013
2	CytokinesIBA 12/2018 - 04/2012
2	CarbohydratesIBA 11/2018 - 10/2012
2	GTP-Binding Proteins (G-Protein)IBA 12/2016 - 01/2016
2	Protons (Proton)IBA 01/2015 - 07/2011
2	Phospholipases (Phospholipase)IBA 04/2014 - 07/2011
2	Carrier Proteins (Binding Protein)IBA 10/2012 - 01/2004
1	LY2584702IBA 01/2022
1	Cyclic NucleotidesIBA 01/2022
1	Protein Kinases (Protein Kinase)IBA 01/2022
1	Metformin (Glucophage)FDA LinkGeneric 03/2020
1	Inositol (Myoinositol)IBA 12/2019
1	Nerve Growth Factors (Neurotrophins)IBA 11/2019
1	Nerve Growth Factor (NGF)IBA 11/2019
1	Nerve Growth Factor Receptor (Nerve Growth Factor Receptor, Low Affinity)IBA 11/2019
1	SphingomyelinsIBA 01/2019
1	Pharmaceutical PreparationsIBA 01/2019
1	Angiopoietin-Like Protein 3IBA 01/2019
1	Antihypertensive Agents (Antihypertensives)IBA 01/2018
1	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2018
1	Ezetimibe (Zetia)FDA Link 01/2018
1	Membrane LipidsIBA 07/2017
1	fibrin fragment D (D-dimer)IBA 01/2017
1	Antiviral Agents (Antivirals)IBA 01/2017
1	Fibrinogen (Factor I)FDA Link 01/2017
1	Blood Coagulation Factors (Coagulation Factor)IBA 01/2017
1	Transcription Factors (Transcription Factor)IBA 01/2016
1	Adenosine Triphosphate (ATP)IBA 01/2016
1	LigandsIBA 01/2016
1	Vitamin D FDA LinkGeneric 04/2014
1	DesmosterolIBA 04/2014
1	EnzymesIBA 04/2014
1	SqualeneIBA 04/2014
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 09/2013
1	Apolipoprotein B-100 (Apo B 100)IBA 09/2013
1	Apolipoproteins E (ApoE)IBA 09/2013
1	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA 08/2013
1	CreatinineIBA 12/2012
1	Vitamin D-Binding ProteinIBA 12/2012
1	Biomarkers (Surrogate Marker)IBA 12/2012
1	MonosaccharidesIBA 10/2012
1	SterolsIBA 10/2012
1	antineoplaston A10 (A 10)IBA 10/2012
1	GlucocorticoidsIBA 09/2012

Therapy/Procedure

5	Therapeutics 01/2022 - 07/2011
1	Bariatric Surgery 11/2017
1	Lasers (Laser) 12/2012